Cardizem, derivative benzothiazepine, has anti-anginal, antiarrhytmic and hypotensive effect. It is prescribed at arterial hypertension: after myocardial infarction, at patients with accompanying stenocardia when beta adrenoblockers, are contraindicative at patients with diabetic nephropathy, in cases when ACE inhibitors are contraindicated; angina of effort, Prinzmetal's angina; prevention of a coronary spasm when carrying out a coronary angiography or operation of aortocoronary shunting.
Calcium channel blocker, a derivative of 1,4-dihydropyridine, has a predominantly cerebrovasculative and antiischemic action. Prescribed for the prevention and treatment of brain ischemia on the background of subarachnoid hemorrhage caused by aneurysm rupture, expressed by brain disfunction in the elderly patients. It can prevent or eliminate spasm of vessels caused by various vasoconstrictor drugs. Improves stability and functional capacity of neurons.
Aceon, which is perindopril - is prescribed at hypertensia, stroke prevention, chronic cardiac failure. Medicine has a vasorelaxant action, it reduces an afterload due to TPR relief, the medicine reduces resistance in vessels of lungs. It is observed increase of the minute volume of myocardium and increase tolerance of myocardium to strain. The medicine has the natriuretic effect and cardioprotection action. The effect of hypotension is observed in 60 minutes after taking the medicine. Arterial pressure loss isn't followed by development of tachycardia. The maximum therapeutic effect is observed in 4-8 hours, the effect is long-term (up to 24 hours). Perindopril improves brain, kidneys, and myocardium circulation, it reduces the needs of cardiomyocytes for oxygen at CHD.
Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
Beclomethasone nasal spray is used to relieve symptoms of sneezing, runny, stuffy, or itchy nose (rhinitis) caused by hay fever, other allergies, or vasomotor (nonallergic) rhinitis. It is also used to prevent nasal polyps (swelling of the lining of the nose) after nasal polyp removal surgery. Beclomethasone nasal spray should not be used to treat symptoms (e.g., sneezing, stuffy, runny, itchy nose) caused by the common cold. Beclomethasone nasal spray is in a class of medications called corticosteroids. It works by blocking the release of certain natural substances that cause allergy symptoms.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
Aggrenox - the combined antiplatelet agent. There are two active ingredients - acetilsalicylic acid and dipiridamol. Action of such combination is caused by different biochemical mechanisms. Aggrenox is prescribed for secondary prevention of ischemic stroke which proceeds as thrombosis. Medicine is also effective for prevention of transitory ischaemic attack.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
