The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Persantine
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 100mg × 30 Pills | $1.01 | $30.19 + Bonus - 4 Pills | - | Add to cart |
| 100mg × 60 Pills | $0.84 | $50.49 + Bonus - 4 Pills | $10.20 | Add to cart |
| 100mg × 90 Pills | $0.79 | $70.80 + Bonus - 7 Pills | $19.80 | Add to cart |
| 100mg × 180 Pills | $0.73 | $131.72 + Bonus - 11 Pills | $50.40 | Add to cart |
| 100mg × 270 Pills | $0.71 | $192.65 + Bonus - 11 Pills | $81.00 | Add to cart |
| 100mg × 360 Pills | $0.70 | $253.57 + Bonus - 11 Pills Free Trackable Delivery | $111.60 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 25mg × 60 Pills | $0.54 | $32.24 + Bonus - 4 Pills | - | Add to cart |
| 25mg × 90 Pills | $0.45 | $40.62 + Bonus - 7 Pills | $8.10 | Add to cart |
| 25mg × 120 Pills | $0.41 | $49.01 + Bonus - 7 Pills | $15.60 | Add to cart |
| 25mg × 180 Pills | $0.37 | $65.76 + Bonus - 11 Pills | $30.60 | Add to cart |
| 25mg × 270 Pills | $0.34 | $90.91 + Bonus - 11 Pills | $54.00 | Add to cart |
| 25mg × 360 Pills | $0.32 | $116.06 + Bonus - 11 Pills | $79.20 | Add to cart |
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Persantine product description
Persantine belongs to the group of drugs affecting the system of blood and blood formation in the human body. The composition includes Dipyridamole - a medical agent used in order to reduce coagulation. Dipyridamole was originally proposed as a coronary-extending (dilating heart vessels) antianginal (anti-anginal) medical preparation. According to experimental data, the drug expands coronary vessels (heart vessels), increases the volume rate of coronary (cardiac) blood flow, improves the supply of myocardium (cardiac muscle) with oxygen. Increases myocardial tolerance to hypoxia (cardiac muscle resistance to oxygen deficiency).
When the circulation in the main coronary vessels is disturbed, this pharmaceutical promotes an improvement in blood circulation in the collateral vasculature (along the blood vessels, by which blood flows around the affected vessel). Under its influence, the total peripheral resistance (total mechanical resistance to blood flow through the vessels) also decreases, the systemic blood pressure decreases somewhat, and cerebral circulation improves.
In the mechanism of the vasodilator effect of Dipyridamole, an increase in the formation of adenosine, one of the participants in the autoregulation of coronary blood flow (regulation by the heart of the rate of blood flow through its vessels) plays a significant role. Dipyridamole is a competitive inhibitor of adenosine deaminase, an enzyme that cleaves adenosine. As coronary dilatant, Dipyridamole is currently limited in use. It is sometimes used for chronic ischemic heart disease.
An important feature of Dipyridamole is its ability to inhibit aggregation (adhesion) of platelets and prevent the formation of clots (blood clots) in the vessels. The drug stimulates the biosynthesis (formation in the body) of prostacyclin and suppresses the synthesis of thromboxanes (biologically active substances taking part in the regulation of vascular tone and the coagulation system of blood).
Persantine safety information
This medical remedy is contraindicated in patients with the prevalent stenosing atherosclerosis of the coronary arteries (a disease of the heart vessels characterized by a decrease in their lumen), thrombocytopenia, intolerance of components, liver and kidney failure in severe form, hemorrhagic syndrome, arterial hypotension, subaortic stenosis of the aorta, cardiac decompensated insufficiency. It is forbidden to prescribe this medication to patients younger than 12 years.
Persantine side effects
According to anti-aggregation activity, Dipyridamole is inferior to Ticlopidine, close to Acetylsalicylic acid. At the same time, it is better tolerated than Acetylsalicylic acid, does not exert ulcerogenic (causing gastric ulcer) action. Dipyridamole is usually well tolerated. In some cases, short-term reddening of the face (vasodilator effect), increased pulse, allergic skin rash.
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Brand Cialis improves erection and helps to achieve a successful sexual intercourse. It is the original medication, intended for use in adult men, who have problems with achieving and maintaining an erection. The pills start acting in 30 to 60 minutes. You can benefit from their effects for up to 36 hours. Therefore, you can take the pills on Saturday evening and enjoy a wonderful weekend, full of sex and pleasant emotions both for you and your partner. The active substance is Tadalafil.
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Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
