Isordil product description

Isordil is the venous, as well as the arterial dilator, which lessens the necessity for myocardium in oxygen, prior and afterload on the heart, has a coronary expansive effect, stabilizes the pressure in a small circle of blood supply, reduces the stress of the walls of the ventricles. Raises the number of the content of nitric oxide in the tissues of blood vessels. The preparation is prescribed during the recovery therapy after myocardial infarction, with the elimination and prevention of angina attacks.

Isordil safety information

Among the restrictions to the remedy usage, there are allergic reactions to the components of the medical remedy, severe arterial hypotension, hyperthyroidism, acute vascular insufficiency, cardiogenic shock, an angle-closure form of glaucoma, age under 18 years (efficacy and safety not established). Pregnant and breastfeeding women should consume Isordil very carefully, only in extreme cases at the urging of a physician.

Special caution should be exercised if the patient has cardiac tamponade and constrictive pericarditis, aortic and/or mitral stenosis, hypertrophic obstructive cardiomyopathy, a tendency to orthostatic reactions (a sharp reduction in blood pressure when the position of the body changes), severe renal failure, hepatic impairment (risk of methaemoglobinaemia) , maladies that are accompanied by increased intracranial pressure (including hemorrhagic stroke, craniocerebral injury), elderly age.

Isordil side effects

At the first consumption or increase in the dosage leads to a decrease in blood pressure, orthostatic hypotension, which can be accompanied by a reflex acceleration in heart rate, inhibition, as well as a sense of weakness and dizziness. At the very beginning of the therapy, the headaches may also appear, which, as a rule, disappear with further consumption of the remedy. There may be a feeling of the slight burning of the tongue, dry mouth. Rarely, nausea, retching, reddening of the face, fever and allergic skin reactions may manifest. In extremely rare cases with a strong reduction in blood pressure, there may be a paradoxical intensification of angina attacks and collapse, sometimes with bradycardia (slowing of heart rate) and syncope (fits with dizziness, associated with cerebral circulatory disorders due to rhythm disturbances heart, primarily due to a significant decrease in the rhythm of the heart). In some cases, exfoliative dermatitis (skin inflammatory disease) may manifest.