Zoloft is an antidepresant stopping the reuptake of serotonin, which is performed by the neurons that isolated it. As a result, the concentration of the neurotransmitter increases in the synaptic cleft and the main cause of depressive states, the serotonin deficiency, is eliminated.
Zoloft
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Product description
Sertralin is an active ingredient in Zoloft. It stops the reuptake of serotonin, which is performed by the neurons that have isolated it. As a result, the concentration of the neurotransmitter increases in the synaptic cleft and the main cause of depressive states, the serotonin deficiency, is eliminated.
The effect on serotonin receptors causes a significant correction of the mental state of patients with depression. It manifests itself in heightening the mood, eliminating phobias, anxious states, reducing feelings of anguish, and reducing appetite. The drug acts on 5-HT receptors. On the reagent of norepinephrine, dopamine is weakly affected. There was no sedative, cardiotoxic effect, anticholinergic effect and stimulation effect. Zoloft does not provoke the formation of dependence. Long-term therapy can lead to a decrease in the activity of adrenaline receptors in the brain.
Indications
Zoloft is prescribed for the treatment and prevention of relapses with:
- Depressive states;
- social phobia;
- obsessive-compulsive disorder (ROC);
- depression with manic conditions;
- panic disorder;
With depression with a sense of anxiety;
- panic disorder with agoraphobia;
- posstraumatic depressive disorders.
Safety information
Zoloft tablets are taken orally. The dose should be prescribed by the doctor and usually is consumed in the morning or evening, once a day. There is no affect on efficacy from Zoloft depending on type of food or the time of your meal.
Contraindications
- Known hypersensitivity to sertraline;
- Simultaneous use of MAO inhibitors and pimozide;
- Pregnancy;
- The period of breastfeeding;
- Children under 6 years;
- Organic diseases of the brain (including delay in mental development);
- Epilepsy;
- Hepatic and / or renal insufficiency;
- Pronounced weight loss.
- On the part of the digestive system: flatulence, nausea, vomiting, diarrhea, constipation, abdominal pain, pancreatitis, dry mouth.
- Cardiovascular: palpitations, tachycardia, hypertension.
- From the musculoskeletal system: arthralgia, muscle cramps.
- From the side nervous system: dyskinesias, akathisia, gnashing of teeth, gait disturbance, involuntary muscular contractions, paresthesia, fainting, drowsiness, headache, migraine, dizziness, tremor, insomnia, anxiety, agitation, hypomania, mania , Hallucinations, euphoria, nightmares, psychosis, decreased libido, suicide, coma.
- On the part of the respiratory system: bronchospasm, yawning.
- From the urinary system: enuresis, urinary incontinence or retention
- On the part of the reproductive system and breast: a violation of sexual function (delay ejaculation, decreased potency), galactorrhea, gynecomastia, menstrual irregularity, priapism.
- On the part of the organs of vision: visual impairment, mydriasis.
- On the part of the endocrine system: Hyperprolactinaemia, hypothyroidism, the syndrome of inadequate secretion of ADH.
- From the hepatic system: hepatitis, jaundice, liver failure.
- Allergic reactions: urticaria, pruritus, anaphylactoid reaction
- Other: weakness, redness of the skin or flushing of the face, ringing in the ears, alopecia, angiooedema, facial edema, periorbital edema, photosensitivity reaction, purpura, increased sweating, decreased appetite (rarely increased), down to anorexia, decrease or increase Body weight, bleeding (including nasal, gastrointestinal or hematuria), peripheral edema, occasionally Stevens-Johnson syndrome and epidermal necrolysis.
- Possible development of leukopenia and thrombocytopenia, as well as increased serum cholesterol levels.
Side effects
- On the part of the digestive system: flatulence, nausea, vomiting, diarrhea, constipation, abdominal pain, pancreatitis, dry mouth.
- Cardiovascular: palpitations, tachycardia, hypertension.
- From the musculoskeletal system: arthralgia, muscle cramps.
- From the side nervous system: dyskinesias, akathisia, gnashing of teeth, gait disturbance, involuntary muscular contractions, paresthesia, fainting, drowsiness, headache, migraine, dizziness, tremor, insomnia, anxiety, agitation, hypomania, mania , Hallucinations, euphoria, nightmares, psychosis, decreased libido, suicide, coma.
- On the part of the respiratory system: bronchospasm, yawning.
- From the urinary system: enuresis, urinary incontinence or retention
- On the part of the reproductive system and breast: a violation of sexual function (delay ejaculation, decreased potency), galactorrhea, gynecomastia, menstrual irregularity, priapism.
- On the part of the organs of vision: visual impairment, mydriasis.
- On the part of the endocrine system: Hyperprolactinaemia, hypothyroidism, the syndrome of inadequate secretion of ADH.
- From the hepatic system: hepatitis, jaundice, liver failure.
- Allergic reactions: urticaria, pruritus, anaphylactoid reaction
- Other: weakness, redness of the skin or flushing of the face, ringing in the ears, alopecia, angiooedema, facial edema, periorbital edema, photosensitivity reaction, purpura, increased sweating, decreased appetite (rarely increased), down to anorexia, decrease or increase Body weight, bleeding (including nasal, gastrointestinal or hematuria), peripheral edema, occasionally Stevens-Johnson syndrome and epidermal necrolysis.
- Possible development of leukopenia and thrombocytopenia, as well as increased serum cholesterol levels.
Combivir - the antiviral combined medicine. Lamivudin and zidovudine are highly effective selective inhibitors of HIV-1 and HIV-2. Lamivudin is a synergist of a zidovudine concerning oppression of replication of HIV.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Brand Cialis improves erection and helps to achieve a successful sexual intercourse. It is the original medication, intended for use in adult men, who have problems with achieving and maintaining an erection. The pills start acting in 30 to 60 minutes. You can benefit from their effects for up to 36 hours. Therefore, you can take the pills on Saturday evening and enjoy a wonderful weekend, full of sex and pleasant emotions both for you and your partner. The active substance is Tadalafil.
An antidepressant from the group of selective inhibitors of serotonin reverse capture. It has thymoanaleptic and stimulating effect. Improves the mood, reduces tension, anxiety and fear, eliminates dysphoria. Doesn’t cause sedation. When taken in high therapeutic doses, it virtually doesn’t effect the function of cardiovascular and other systems.
Glycomet is a drug that is also called Biguanide. It’s a hypoglycemic agent that reduces the concentration of glucose in the blood by suppressing gluconeogenesis in the liver, reducing the absorption of glucose from the digestive tract, and increasing its utilization in tissues in patients with diabetes mellitus. The drug reduces the concentration of Thyroglobulin, cholesterol, and LDL (determined on an empty stomach) in the blood serum and does not change the concentration of lipoproteins of other densities. Glycomet stabilizes or reduces body weight. The pills don’t cause hypoglycemic reactions and improve the fibrinolytic properties of the blood.
Grifulvin V - the antifungal antibiotic, which is taken at mycoses of skin, hair and nails, and effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of structure of mitotic spindle and synthesis of a cell wall in chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.
Cleocin has bacteriostatic and bactericidal activity depending on concentration of drug, infectious process and condition of an organism of the patient. Active against aerobic and anaerobic streptococcus (except for enterococci), the majority of staphylococcus except for methicillin-resistant strains, bacteroids except for Bacteroides melaninogenicus, spindle-shaped bacteria
Isoptin is a calcium ion antagonist of the phenylalkylamine group. It improves myocardial perfusion, eliminates coronary spasm, reduces myocardial oxygen demand. It is used for diseases of the cardiovascular system.
Cardioselective beta-1 blocker. Does not have a membrane-stabilizing action and does not have an internal AGR. Has antihypertensive, anti-angiogenic and antiarrhythmic action. It is used for IHD, angina pectoris, unstable angina, myocardial infarction, arterial hypertension, hypertensive crisis, tachycardia, thyrotoxicosis.
Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
Silagra tablets do a highly effective job of relaxing the musculature in the phallus. The drug increases the movement of blood in caverns of the erectile tissue by vasodilatory activity. It belongs to the category of medicines distributed as PDE5 blockers. Similarly to Viagra, these pills contain sildenafil citrate – a substance that mainly finds use as a cure for erectile disorders. Silagra mainly interacts with the circulatory function and requires an adequate sexual stimulation to set in action. Its effect can be felt in 30-40 minutes, resulting in about 4 hours of strong erection.
Levitra Soft - convenient chewable tablets, also act as their famous analogue - Brand Levitra, but cost several times cheaper. This form of generic tablet has a pleasant taste, it does not need to be taken with water. The effect occurs maximum in 15 minutes after taking the drug and lasts about 12 hours. The tablet can be combined with alcohol and fatty foods. The number of side effects is minimal and they are manifested only in cases of an overdose.
Inhibitor of H+-K+-ATP, the dextrorotatory isomer of omeprazole. Reduces the secretion of hydrochloric acid in the stomach by specific inhibition of the proton pump in parietal cells. The therapeutic use includes gastroesophageal reflux disease: erosive reflux esophagitis (treatment), prevention of relapse in patients with healed esophagitis, symptomatic treatment of GERD.
Diamox weak diuretic which is taken at edematous syndrome, craniocereberal hypertensia, glaucoma, epilepsy and mountain disease. Inhibits carbonic anhydrase in a proximal gyrose tubule of nephron, increases removal with urine Na+, K+, hydrocarbonate, does not influence Cl- egestion, alkalinizes urine.
Dilantin - antiepileptic drug without the expressed somnolent effect; it has membrane stabilizing, antiarrhytmic and hypotensive effect. It is taken if it is diagnosed activated epilepsy, supraventricular and ventricular disturbances of a heart rhythm caused by intoxication cardiac glycosides.
Dutas is a mix of two medicines: dutasteride and tamsulosin hydrochloride. The drugs have complementary mechanisms of action, due to which there is a rapid weakening of urination. It reduces the risk of retention of the urine. It is not anticipated that the pharmacodynamic reactions of a fixed dosage mix of dutasteride-tamsulosin differ from those obtained with the simultaneous use of dutasteride and tamsulosin as separate elements. Dutasteride inhibits the activity of both the 1st and 2nd type of isoenzymes. DHT is an androgen that is responsible for prostate and the increase of BPH. It inhibits the activity of adrenoreceptors.
Eulexin - antineoplastic medicine, anti-androgen. Competitively blocks interaction of androgens with their cellular receptors; interferes with manifestation of biological effects of male sex hormones in androgensensetive organs. It is taken for palliative treatment of cancer.
Keppra - antiepileptic drug, the mechanism of action is unclear, it does not alter normal synaptic transmission. Effective in both focal and epilepsy (epileptiform manifestations, photo paroxysmal reaction).
Methotrexate belongs to the group of antimetabolites with cytostatic activity. It inhibits the conversion of dihydrofolic acid into tetrahydrofolic acid. Thymidylic acid and purine synthesis are disrupted, which, in turn, suppresses DNA synthesis and cell division. The maximum absorption of the medicine is observed after 30 to 60 minutes. The drug is metabolized by enzymes of the intestinal microflora, hepatocytes, and other cells.
Arcoxia - analgesic and anti-inflammatory drug of a group of highly selective cyclooxygenase-2 inhibitors. The drug has anti-inflammatory, analgesic and antipyretic effect.
Toradol - tablets containing 5 and 10 mg of ketorolac tromethamine as an active substance. It has a pronounced analgesic, as well as antipyretic and anti-inflammatory action, the mechanism of which is associated with inhibition of the synthesis of prostaglandins. Suppresses the aggregation of platelets.
The medicine is an analeptic aimed to treat sleepiness connected with narcolepsy (unexpected sleepiness and drowsiness). Management of quality supervision food and drug administration is also approved for the treatment of sleep disorders associated with shift work shifts. In the first two weeks, the allergies may appear. The use of Modafinil is also popular for non-medical purposes as a relatively safe stimulant.
The active substance of the medicine is aimed at reducing the release of the hormone Prolactin increasing libido and the rate of recovery after a sexual relationship. They also reduce blood pressure. Cabgolin acts as a modern substitute for Bromocriptine and differs from it by its harmlessness and greater efficiency. Cabgolin has a liquidating effect on steroids, which include Trenbolone and DECA-Durabolin. The inhibition of the production of Prolactin at the same time contributes to the elimination of fluid retention in the tissues.
Doryx MPC (doxycycline hyclate) delayed-release tablets for oral use, contain doxycycline hyclate, a tetracycline class drug synthetically derived from oxytetracycline, in a delayed-release formulation consisting of pellets with a modified polymer enteric coat that has increased acid resistance.
