ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below:
Eryc
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| 250mg × 120 Pills | $0.82 | $98.13 | $45.60 | Add to cart |
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| 250mg × 300 Pills | $0.74 | $222.33 Free Trackable Delivery | $138.00 | Add to cart |
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Upper respiratory tract infections of mild to moderate degree caused by Streptococcus pyogenes, Streptococcus pneumoniae, or Haemophilus influenzae (when used concomitantly with adequate doses of sulfonamides, since many strains of H. influenzae are not susceptible to the erythromycin concentrations ordinarily achieved).
Lower respiratory tract infections of mild to moderate severity caused by Streptococcus pneumoniae or Streptococcus pyogenes.
Listeriosis caused by Listeria monocytogenes.
Pertussis (whooping cough) caused by Bordetella pertussis. Erythromycin is effective in eliminating the organism from the nasopharynx of infected individuals rendering them noninfectious. Some clinical studies suggest that erythromycin may be helpful in the prophylaxis of pertussis in exposed susceptible individuals.
Respiratory tract infections due to Mycoplasma pneumoniae.
Skin and skin structure infections of mild to moderate severity caused by Streptococcus pyogenes or Staphylococcus aureus (resistant staphylococci may emerge during treatment).
Diphtheria: Infections due to Corynebacterium diphtheriae, as an adjunct to antitoxin, to prevent establishment of carriers and to eradicate the organism in carriers.
Erythrasma: In the treatment of infections due to Corynebacterium minutissimum.
Syphilis caused by Treponema pallidum: Erythromycin is an alternate choice of treatment for primary syphilis in penicillin-allergic patients. In primary syphilis, spinal fluid examinations should be done before treatment and as part of follow-up after therapy.
Intestinal amebiasis caused by Entamoeba histolytica (oral erythromycins only). Extraenteric amebiasis requires treatment with other agents.
Acute pelvic inflammatory disease caused by Neisseria gonorrhoeae: Erythromycin lactobionate for injection, USP followed by erythromycin base orally, as an alternative drug in treatment of acute pelvic inflammatory disease caused by N. gonorrhoeae in female patients with a history of sensitivity to penicillin. Patients should have a serologic test for syphilis before receiving erythromycin as treatment of gonorrhea and a follow-up serologic test for syphilis after 3 months.
Erythromycins are indicated for the treatment of the following infections caused by Chlamydia trachomatis: conjunctivitis of the newborn, pneumonia of infancy, and urogenital infections during pregnancy. When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of uncomplicated urethral, endocervical, or rectal infections in adults due to Chlamydia trachomatis.
When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of nongonococcal urethritis caused by Ureaplasma urealyticum.
Legionnaires' Disease caused by Legionella pneumophila. Although no controlled clinical efficacy studies have been conducted, in vitro and limited preliminary clinical data suggest that erythromycin may be effective in treating Legionnaires' Disease.
Prophylaxis
Prevention of Initial Attacks of Rheumatic Fever: Penicillin is considered by the American Heart Association to be the drug of choice in the prevention of initial attacks of rheumatic fever (treatment of Streptococcus pyogenes infections of the upper respiratory tract, e.g., tonsillitis or pharyngitis). Erythromycin is indicated for the treatment of penicillin-allergic patients.3 The therapeutic dose should be administered for ten days.
Prevention of Recurrent Attacks of Rheumatic Fever: Penicillin or sulfonamides are considered by the American Heart Association to be the drugs of choice in the prevention of recurrent attacks of rheumatic fever. In patients who are allergic to penicillin and sulfonamides, oral erythromycin is recommended by the American Heart Association in the long-term prophylaxis of streptococcal pharyngitis (for the prevention of recurrent attacks of rheumatic fever).3
To reduce the development of drug-resistant bacteria and maintain the effectiveness of ERYC and other antibacterial drugs, ERYC should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Overdosage
In case of overdosage, erythromycin should be discontinued. Overdosage should be handled with the prompt elimination of unabsorbed drug and all other appropriate measures.
Erythromycin is not removed by peritoneal dialysis or hemodialysis.
Storage
Store at controlled room temperature 15° C to 30° C (59° F to 86° F).
Safety information
Warnings
Hepatotoxicity
There have been reports of hepatic dysfunction, including increased liver enzymes, and hepatocellular and/or cholestatic hepatitis, with or without jaundice, occurring in patients receiving oral erythromycin products.
QT Prolongation
Erythromycin has been associated with prolongation of the QT interval and infrequent cases of arrhythmia. Cases of torsades de pointes have been spontaneously reported during postmarketing surveillance in patients receiving erythromycin. Fatalities have been reported. Erythromycin should be avoided in patients with known prolongation of the QT interval, patients with ongoing proarrhythmic conditions such as uncorrected hypokalemia or hypomagnesemia, clinically significant bradycardia, and in patients receiving Class IA (quinidine, procainamide) or Class III (dofetilide, aminodarone, sotalol) antiarrhythmic agents. Elderly patients may be more susceptible to drug-associated effects on the QT interval.
Syphilis in pregnancy
There have been reports suggesting that erythromycin does not reach the fetus in adequate concentration to prevent congenital syphilis. Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen.
Clostridium difficile-associated diarrhea
Clostridium difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including ERYC Capsules, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.
C. difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of C. difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents.
If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C. difficile, and surgical evaluation should be instituted as clinically indicated.
Drug Interactions
Serious adverse reactions have been reported in patients taking erythromycin concomitantly with CYP3A4 substrates. These include colchicine toxicity with colchicine; rhabdomyolysis with simvastatin, lovastatin, and atorvastatin; and hypotension with calcium channel blockers metabolized by CYP3A4 (for example, verapamil, amlodipine, diltiazem).
There have been post-marketing reports of colchicine toxicity with concomitant use of erythromycin and colchicine. This interaction is potentially life-threatening, and may occure while using both drugs at their recommended doses.
Rhabdomyolysis with or without renal impairment has been reported in seriously ill patients receiving erythromycin concomitantly with lovastatin. Therefore, patients receiving concomitant lovastatin and erythromycin should be carefully monitored for creatine kinase (CK) and serum transaminase levels.
Disclaimer
The information on this page is not intended to be a substitute for professional medical advice. Do not use this information to diagnose or treat your problem without consulting your doctor.
Side effects
The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Symptoms of hepatitis, hepatic dysfunction and/or abnormal liver function test results may occur.
Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment.
Erythromycin has been associated with QT prolongation and ventricular arrhythmias, including ventricular tachycardia and torsade de pointes.
Allergic reactions ranging from urticaria to anaphylaxis have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported rarely.
There have been reports of interstitial nephritis coincident with erythromycin use.
There have been reports of pancreatitis and convulsions.
There have been isolated reports of reversible hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.
Furosemide - «Loopback" diuretic; causes quickly coming, severe and short-term diuresis. Has natriuretic and chloro effects, increases clearance of K+, Ca2+, Mg2+. It is taken at edematous syndrome, cirrhosis, diseases of kidneys, heavy course of arterial hypertension and hypercalcemia.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Brand Cialis improves erection and helps to achieve a successful sexual intercourse. It is the original medication, intended for use in adult men, who have problems with achieving and maintaining an erection. The pills start acting in 30 to 60 minutes. You can benefit from their effects for up to 36 hours. Therefore, you can take the pills on Saturday evening and enjoy a wonderful weekend, full of sex and pleasant emotions both for you and your partner. The active substance is Tadalafil.
Combivir - the antiviral combined medicine. Lamivudin and zidovudine are highly effective selective inhibitors of HIV-1 and HIV-2. Lamivudin is a synergist of a zidovudine concerning oppression of replication of HIV.
Enhances the protective mechanisms of the gastric mucosa by increasing the formation of gastric mucus and of glycoproteins in it, as well as stimulation of bicarbonate secretion and endogenous Pg synthesis in it, promotes healing of its injuries (including scarring of stress ulcers), and the cessation of gastrointestinal bleeding. The list of indications includes: gastric ulcer and duodenal ulcer, hyperacidity of gastric juice, heartburn (associated with hyperchlorhydria), symptomatic and stress ulcers of the gastrointestinal tract.
Seroflo represents a family of remedies ensuring alleviation of the symptoms of ordinary asthma. The medication’s ingredients include fluticasone propionate and salmeterol xinafoate that constitute many time-tested treatments of protracted bronchitis and acute pulmonary glands disorders. The corticosteroid nature of fluticasone plus salmeterol as a long-performing beta-agonist help to eliminate asthma attacks and provide anti-inflammatory action. Patients can breathe with ease and get relieved from obstructing mucus in their airways. Seroflo works as a preventive agent and cannot terminate an asthma bout that has already begun.
Effexor - antidepressant. Active ingredient - venlafaxine and its main metabolite O-desmetilvenlafaxine which are strong inhibitors of the return serotonin reuptake and noradrenaline and weak inhibitors of the return capture of a dopamine. It is considered that the mechanism of antidepressive action is connected with ability of drug to strengthen transfer of nervous impulses in CNS.
Glycomet is a drug that is also called Biguanide. It’s a hypoglycemic agent that reduces the concentration of glucose in the blood by suppressing gluconeogenesis in the liver, reducing the absorption of glucose from the digestive tract, and increasing its utilization in tissues in patients with diabetes mellitus. The drug reduces the concentration of Thyroglobulin, cholesterol, and LDL (determined on an empty stomach) in the blood serum and does not change the concentration of lipoproteins of other densities. Glycomet stabilizes or reduces body weight. The pills don’t cause hypoglycemic reactions and improve the fibrinolytic properties of the blood.
Grifulvin V - the antifungal antibiotic, which is taken at mycoses of skin, hair and nails, and effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of structure of mitotic spindle and synthesis of a cell wall in chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Cleocin has bacteriostatic and bactericidal activity depending on concentration of drug, infectious process and condition of an organism of the patient. Active against aerobic and anaerobic streptococcus (except for enterococci), the majority of staphylococcus except for methicillin-resistant strains, bacteroids except for Bacteroides melaninogenicus, spindle-shaped bacteria
Isoptin is a calcium ion antagonist of the phenylalkylamine group. It improves myocardial perfusion, eliminates coronary spasm, reduces myocardial oxygen demand. It is used for diseases of the cardiovascular system.
Cardioselective beta-1 blocker. Does not have a membrane-stabilizing action and does not have an internal AGR. Has antihypertensive, anti-angiogenic and antiarrhythmic action. It is used for IHD, angina pectoris, unstable angina, myocardial infarction, arterial hypertension, hypertensive crisis, tachycardia, thyrotoxicosis.
Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
Levitra Soft - convenient chewable tablets, also act as their famous analogue - Brand Levitra, but cost several times cheaper. This form of generic tablet has a pleasant taste, it does not need to be taken with water. The effect occurs maximum in 15 minutes after taking the drug and lasts about 12 hours. The tablet can be combined with alcohol and fatty foods. The number of side effects is minimal and they are manifested only in cases of an overdose.
Inhibitor of H+-K+-ATP, the dextrorotatory isomer of omeprazole. Reduces the secretion of hydrochloric acid in the stomach by specific inhibition of the proton pump in parietal cells. The therapeutic use includes gastroesophageal reflux disease: erosive reflux esophagitis (treatment), prevention of relapse in patients with healed esophagitis, symptomatic treatment of GERD.
Diamox weak diuretic which is taken at edematous syndrome, craniocereberal hypertensia, glaucoma, epilepsy and mountain disease. Inhibits carbonic anhydrase in a proximal gyrose tubule of nephron, increases removal with urine Na+, K+, hydrocarbonate, does not influence Cl- egestion, alkalinizes urine.
Eulexin - antineoplastic medicine, anti-androgen. Competitively blocks interaction of androgens with their cellular receptors; interferes with manifestation of biological effects of male sex hormones in androgensensetive organs. It is taken for palliative treatment of cancer.
Keppra - antiepileptic drug, the mechanism of action is unclear, it does not alter normal synaptic transmission. Effective in both focal and epilepsy (epileptiform manifestations, photo paroxysmal reaction).
Mentat improves mental functions by modulating cholinergic neurotransmission and by restoring the activity of the frontal cortical muscarinic and cholinergic receptors. It improves mental activity, memory duration, concentration ability, reduces tension and increases the detention to stress. The drug is aimed to lower the level of tribulin. It also improves the quality of attention and stabilizes behavioral reactions. Mentat provides important assistance in Parkinson's disease. Mentat improves articulation and corrects speech defects. It promotes the mental development of children.
Methotrexate belongs to the group of antimetabolites with cytostatic activity. It inhibits the conversion of dihydrofolic acid into tetrahydrofolic acid. Thymidylic acid and purine synthesis are disrupted, which, in turn, suppresses DNA synthesis and cell division. The maximum absorption of the medicine is observed after 30 to 60 minutes. The drug is metabolized by enzymes of the intestinal microflora, hepatocytes, and other cells.
Toradol - tablets containing 5 and 10 mg of ketorolac tromethamine as an active substance. It has a pronounced analgesic, as well as antipyretic and anti-inflammatory action, the mechanism of which is associated with inhibition of the synthesis of prostaglandins. Suppresses the aggregation of platelets.
The medicine is an analeptic aimed to treat sleepiness connected with narcolepsy (unexpected sleepiness and drowsiness). Management of quality supervision food and drug administration is also approved for the treatment of sleep disorders associated with shift work shifts. In the first two weeks, the allergies may appear. The use of Modafinil is also popular for non-medical purposes as a relatively safe stimulant.
Naprosyn is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects associated with non-selective inhibition of Cyclooxygenase-1 and Cyclooxygenase-2 activity.
The active substance of the medicine is aimed at reducing the release of the hormone Prolactin increasing libido and the rate of recovery after a sexual relationship. They also reduce blood pressure. Cabgolin acts as a modern substitute for Bromocriptine and differs from it by its harmlessness and greater efficiency. Cabgolin has a liquidating effect on steroids, which include Trenbolone and DECA-Durabolin. The inhibition of the production of Prolactin at the same time contributes to the elimination of fluid retention in the tissues.
Alkeran is a medicine used to treat the symptoms of Multiple Myeloma and Ovarian Cancer. Alkeran may be used alone or with other medications.
Alkeran belongs to a class of drugs called Antineoplastics, Alkylating.
It is not known if Alkeran is safe and effective in children.
The active component of the medicine is highly purified synthesized Bimatoprost.It is used for the growth of eyelashes, increasing their number, length, and density. The active ingredient Bimat contains biologically active lipids which promote microcirculation of hair follicles accelerating their natural growth. If your lashes are tired of the procedure, the recovery effect is achieved after 3-4 weeks, and the maximum result after 4 months of application. Amazing means Bimat gives a stunning volume and strength to weakened lashes.
