Chloromycetin - the Antibiotic of a broad spectrum of activity. The mechanism of antimicrobic action is connected with disturbance of protein synthesis of microorganisms. It has bacteriostatic action. It is active concerning gram-positive bacteria. Chloromycetin is active concerning the strains steady against penicillin, streptomycin, streptocides.
Chloromycetin
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 250mg × 60 Pills | $0.62 | $37.07 + Bonus - 4 Pills | - | Add to cart |
| 250mg × 90 Pills | $0.53 | $47.39 + Bonus - 7 Pills | $8.10 | Add to cart |
| 250mg × 120 Pills | $0.48 | $57.69 + Bonus - 7 Pills | $16.80 | Add to cart |
| 250mg × 180 Pills | $0.44 | $78.30 + Bonus - 11 Pills | $32.40 | Add to cart |
| 250mg × 270 Pills | $0.40 | $109.22 + Bonus - 11 Pills | $59.40 | Add to cart |
| 250mg × 360 Pills | $0.39 | $140.14 + Bonus - 11 Pills | $82.80 | Add to cart |
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Chloromycetin Product Description
Drug Uses
Chloromycetin is an antibiotic with a broad spectrum of antimicrobial action. The mechanism of action of this antibiotic is based on the violation of the process of protein synthesis and life-sustaining activity in the microbial cell.
Chloromycetin antibiotic has a high antimicrobial activity and is effective against many gram-positive and gram-negative bacteria, meningococcal infection, typhoid causative agents, dysentery and rickettsial infections.
Clinical studies have shown that resistance of microorganism to Chloromycetin develops slowly. This antibiotic well penetrates, so is distributed in the body tissues and fluids.
Chloromycetin can be prescribed for children and adults for the treatment of such infections and diseases as:
- pneumonia
- septicaemia
- typhoid fever
- eye infections
- salmonellosis
- granuloma inguinale
- bacterial meningitis
- chlamydial infection
- urinary tract infections
The maximum antibacterial effect of Chloromycetin is reached within 1.5-2 hours after oral administration and lasts for about 5 hours. The antibiotic dose is prescribed according to the patient’s body weight.
Typically, the daily dose of Chloromycetin for adults is 50mg of the antibiotic per each kg of body weight, divided into 4 doses. Children's daily dose of Chloromycetin is 25mg / kg of body weight, divided into 4 doses.
Missed dose
As soon as you remember that you have missed a Chloromycetin dose, immediately take the regular dose. If it is almost time for the next dose of the antibiotic, do not take a double dose to make up the previous one. If to take two doses of Chloromycetin at the same time, this may increase the chance of side effects.
More Information
When prescribing the antibiotic to the patients with renal or hepatic impairment, the therapeutic dose of Chloromycetin should be reduced. Due to the high toxicity of this antibiotic, it should not be used to treat minor infections, sore throat, cold, flu, and bacilli carriers.
Do not take this antibiotic for longer than the disease therapy requires and avoid the repeated courses of treatment with Chloromycetin as long as possible. In long-term antibiotic therapy, examination of the peripheral blood smear should be systematically conducted.
Storage
Chloromycetin should be protected from excessive heat and moisture, as well as kept at a temperature up to 30 °C.
Chloromycetin Safety Information
Warnings
If bone marrow failure, anemia and thrombocytopenia develop when using Chloromycetin, the use of this antibiotic should be discontinued. The simultaneous use of Chloromycetin with other antibiotics (erythromycin, lincomycin) may lead to the growth of non-susceptible bacteria and development of antimicrobial resistance.
Disclaimer
This Chloromycetin review contains materials that should not be considered as a substitute for professional consultation with an infectious disease specialist or therapist. The online pharmacy expressly disclaims any liable or responsible for any kind of loss, damage or claim, which can arise from incorrect using information on antimicrobial therapy and Chloromycetin.
Chloromycetin Side Effects
After using Chloromycetin, different adverse events may occur, the most severe of which are: headache, mild depression, mental confusion, delirium and myelotoxicity. Less often, Chloromycetin may cause dermatological disorders (such as urticaria, fever and rash). During the long-term antibiotic therapy, Chloromycetin may cause optic / peripheral neuritis, blood dyscrasias or maculopapular dermatitis. If these adverse events are severely expressed, the cessation of Chloromycetin can be recommended.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
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