A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.

Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.

The drug is a prodrug and is activated in the acidic environment of the secretory tubules in the parietal cells. It reduces basal and stimulated secretion regardless of the nature of the stimulus. Prescribed in case of erosive ulcerative diseases of the gastrointestinal tract and eradication of Helicobacter pylori in infected patients with gastric and duodenal ulcer.