Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.

Doxycycline is a semi-synthetic antibiotic of a broad spectrum of tetracyclines. Causes bacteriostatic action by suppressing protein synthesis of pathogens as a result of blocking the aminoacyl transport RNA (tRNA) with the "information RNA (rRNA) complex" ribosome.

Erythromycin is a macrolide antibiotic of bacteriostatic action. In high concentrations and relatively high-sensitivity microorganisms may have a bactericidal effect.

Cleocin has bacteriostatic and bactericidal activity depending on concentration of drug, infectious process and condition of an organism of the patient. Active against aerobic and anaerobic streptococcus (except for enterococci), the majority of staphylococcus except for methicillin-resistant strains, bacteroids except for Bacteroides melaninogenicus, spindle-shaped bacteria