An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.

Gyne-Lotrimin - antifungal medicine from group of derivatives of imidazole for external and local (intravaginal) use, reduces synthesis of ergosterol which is a component of a cellular membrane of a microbic wall and leads to change of its structure and properties.